Are you aging faster than you would like due to telomere shortening?
Current research shows that telomere shortening contributes to cellular aging and susceptibility to metabolic disorders and chronic disease.1-6 According to scientific research, telomere shortening may contribute to aging and age-related conditions. Telomeres are segments of DNA found at the ends of chromosomes. They can be prematurely shortened when exposed to environmental chemicals, oxidation, inflammation, and stress. This leads to DNA damage and contributes to early cell death.7-9
Shorter telomeres have been associated with cardiovascular disease, inflammatory disorders, metabolic syndrome, diabetes, cognitive decline, and other chronic degenerative conditions associated with aging.
- Neurological conditions such as Cognitive impairment, chronic stress 10, 11
- • Metabolic disorders such as Diabetes, glucose intolerance, obesity 12, 13
- • Cardiovascular diseases such as Atherosclerosis, coronary artery disease 14-16
- • Musculoskeletal disorders such as Osteoarthritis, rheumatoid arthritis 17, 18
- • Immune-related conditions such as Hepatitis C, cancer, autoimmune disorders 19-21
Inflammation, Aging, and its association with Telomeres
Inflammation is associated with aging and telomere shortening. Telomeres become shorter after each cell division until eventually chromosomal DNA reaches a critical point at which the cell can no longer divide (known as the Hayflick limit).22The loss of this protective telomere “armor” renders DNA vulnerable to damage and may result in an individual’s increased risk for accelerated aging and associated health conditions. If telomeres are maintained, then termination of cell division (senescence) and programmed cell death (apoptosis) can be delayed. The test analyzes your average telomere length in white blood cells compared to the normal reference range for your age-matched population.
Easy to understand color-coded test results compare telomere length to reference ranges of your age-matched population. Graphic version of the result allows for easier understanding and analysis.
About our lab
Cell Science Systems, Corp. is a specialty clinical laboratory that develops and performs laboratory testing in immunology and cell bioligy supporting the personalized treatment and prevention of chronic disease. Cell Science Systems, Corp. operates a CLIA certified laboratory and is an FDA inspected and registered, cGMP medical device manufacturer meeting ISO EN13485 2012 standards. 3, 17-19
Committed to quality
Cell Science Systems fulfills high quality standards in accordance with state, federal and international regulations.
- • CLIA-ID#10D0283906
- • CE Marked. TUV Certified and safety monitored
- • Supported by the EU and the State of Brandenburg
- • ISO 13485:2003 + AC:2012
To view the references or learn more, visit:
TEST ID: Telomere Length Testing
DESCRIPTION: Testing of the average telomere length in lymphocytes
Telomere shortening is associated with ageing, mortality and age related diseases. Shorter telomeres have been linked to cardiovascular disease, some cancers, osteoporosis, dementia, diabetes, and other chronic degenerative diseases of aging conditions.
The test is designed for anyone interested in optimal health, age management and in knowing their telomere length as it relates to being within or outside the normal reference range for their chronological age.
COLLECTION Whole blood in sodium citrate tube.
SPECIMEN STABILITY Must be received within 24 hrs (optimal) to 48 hrs of collection.
REJECTION CRITERIA Blood sample is over 48 hours old; hemolyzed, icteric, and lipemic specimens; improper anticoagulant or no anticoagulant used.
Quantitative real-time PCR (qPCR)
Results reported as Telomere Value that is compared to the range of values found to be present in the population of the same age group. Graphic version of the result presentation allows for easier understanding and analysis. Results within the green area (±1SD) and yellow area (±2SD) of the graph are considered to be within normal range. Results in the red area are considered to be outside of the normal range.